Regenerating Intervertebral Discs with Chitosan Hydrogels

Adoungotchodo, Atma, Alinejad, Yasaman, Grant, Michael, Epure, Laura M., Antoniou, John, Mwale, Fackson et Lerouge, Sophie. 22 January 2019. « Regenerating Intervertebral Discs with Chitosan Hydrogels ». [Research article]. Substance ÉTS.

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Abstract

Cell therapy using cells encapsulated in injectable matrices is a promising technique for the minimally invasive treatment of intervertebral disc degeneration, one of the major causes of back pain which affects 19% of the world’s population. However, this therapeutic approach is limited by the generally low mechanical properties of injectable matrices. This study demonstrates the potential of new injectable chitosan hydrogels formulations with interesting mechanical properties for the regeneration of intervertebral discs, in particular their central part called nucleus pulposus (NP).

Item Type:	Non-peer reviewed article published in a journal or magazine
Refereed:	No
Professor:	Professor Lerouge, Sophie
Affiliation:	Génie mécanique
Date Deposited:	26 Mar 2019 16:05
Last Modified:	17 Jan 2020 20:48
URI:	https://espace2.etsmtl.ca/id/eprint/18306

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