Marcolini, Sofia, Rojczyk, Philine, Seitz-Holland, Johanna, Koerte, Inga K., Alosco, Michael L. et Bouix, Sylvain.
2023.
« Posttraumatic stress and traumatic brain injury: Cognition, behavior, and neuroimaging markers in Vietnam veterans ».
Journal of Alzheimer's Disease, vol. 95, nº 4.
pp. 1427-1448.
Compte des citations dans Scopus : 2.
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Résumé
Background: Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are common in Veterans and linked to behavioral disturbances, increased risk of cognitive decline, and Alzheimer’s disease. Objective: We studied the synergistic effects of PTSD and TBI on behavioral, cognitive, and neuroimaging measures in Vietnam war Veterans. Methods: Data were acquired at baseline and after about one-year from male Veterans categorized into: PTSD, TBI, PTSD+TBI, andVeteran controls without PTSD or TBI.We applied manual tractography to examine white matter microstructure of three fiber tracts: uncinate fasciculus (N= 91), cingulum (N= 87), and inferior longitudinal fasciculus (N= 95). ANCOVAs were used to compareVeterans’ baseline behavioral and cognitive functioning (N= 285), white matter microstructure, amyloid-� (N= 230), and tau PET (N= 120). Additional ANCOVAs examined scores’ differences from baseline to follow-up.
| Type de document: | Article publié dans une revue, révisé par les pairs |
|---|---|
| Professeur: | Professeur Bouix, Sylvain |
| Affiliation: | Génie logiciel et des technologies de l'information |
| Date de dépôt: | 16 nov. 2023 15:52 |
| Dernière modification: | 31 janv. 2024 20:15 |
| URI: | https://espace2.etsmtl.ca/id/eprint/28016 |
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